Senior or Principal Scientist, Protein Engineering, Biologics Drug Discovery Stealth Biotech Startup Job at Jobleads-US, San Francisco, CA

SmszWjdZcitPTG1rMDFSK3pkUTNZN2c0M2c9PQ==
  • Jobleads-US
  • San Francisco, CA

Job Description

We are seeking a highly motivated and ambitious Protein Engineer to join our stealth-stage biotech startup. The successful candidate will develop novel biologics for geriatric disorders. This is a unique opportunity to shape the direction of our protein engineering efforts. We are looking for someone who has broad familiarity with modern antibody discovery and protein engineering techniques, strong problem-solving skills, and a willingness to learn quickly. Location: San Francisco, CA Key Responsibilities: ● Lead antibody discovery campaigns conducted externally with CROs partners and evolve leads internally using phage or yeast display libraries ● Use protein engineering techniques to develop protein fusions with optimized expression, pharmacokinetics, and developability properties ● Develop and optimize moderate- and high-throughput assays to screen and characterize engineered protein variants

  • Analyze large datasets from next-generation sequencing of protein and antibody libraries
  • Characterize lead candidates using biochemical, cell-based, and in vivo assays
  • Collaborate closely with the founders to drive the project forward
Qualifications: ● PhD in Protein Engineering, Biochemistry, or related field with at least 5 years of post-graduate experience. Hiring level will be commensurate with experience and skillset ● Experience assembling and screening yeast or phage display libraries, preferably incorporating NGS-based workflows
  • Background in biochemistry, molecular biology, and protein expression & purification
  • Familiarity with analytical methods for characterizing the biophysical properties of
proteins (e.g., SE-HPLC, DLS, DSF , SPR, BLI, etc)
  • Characterize protein function with ELISAs, flow cytometry, and activity reporter assays
  • Proficiency in data analysis and programming (e.g. Python, R)
  • Strong communication and collaboration abilities
  • Excellent problem-solving skills and ability to work independently
  • Entrepreneurial mindset and enthusiasm for working in a fast-paced startup environment
The ideal candidate will be drawn to hard problems: proactive, creative, and excited for new challenges. You should be comfortable wearing multiple hats and adapting as our needs evolve. This role offers significant opportunities for growth and leadership as we expand our team. If you are passionate about protein engineering and developing new drugs to treat geriatric diseases, we want to hear from you! #J-18808-Ljbffr Jobleads-US

Job Tags

Similar Jobs

Nesco Resource

Quality Control Analyst Job at Nesco Resource

 ...A well-established Biotech company is looking for several entry-level QC Analysts to support its team! These are all 12-month temporary roles, with strong potential for permanent hire. Great opportunity for recent graduates in the life sciences! Role Details:... 

Walmart

Distribution Center Supervisor Job at Walmart

 ...; monitoring associate compliance to policies and procedures; distributing and maintaining procedures and supporting documentation.Identify...  ...standards of integrity, ethics and compliance, models the Walmart values to support and foster our culture; holds oneself and others... 

Medicorp, Inc

Physician / Radiology / Michigan / Permanent / seeking an Interventional Radiologist provider to join our team.- A growing multi-specialty Job Job at Medicorp, Inc

Interventional Radiologist Opportunity in Michigan's Upper Peninsula Seeking an Interventional Radiologist provider to join our team. - A growing multi-specialty practice inclusive of 1 Interventional Radiologist, 1 Cardiologists and 10 APPs. Our major service lines include... 

MultiTracks.com

Digital Content & Social Media Coordinator Job at MultiTracks.com

 ...seeking a detail-oriented Digital Content & Social Media Coordinator to join our marketing team....  ...to attend in-person meetings or project work in-office Bonus but not required...  ...schedule and needs.~ Remote / work from home days (for in-office employees)~... 

Everlight Solar

Junior Personal Coordinator Job at Everlight Solar

 ...variety of administrative tasks including data entry, assisting in the planning and execution...  .... This is a In-person, full-time, entry level position. Travel required. Looking for...  ...Wears Prada assistant! Must own a Mac computer and be fluent with the Apple ecosystem of...